Main Causes of Oral Ulceration
Trauma:
- Sharp Teeth or Restorations
- (Electrical) Appliances
- Non-Accidental Injury
- Self-inflicted
- Iatrogenic
Burns:
- Heat
- Cold
- Chemical
- Radiation
- Electric
Recurrent Aphthæ (and Behçet Syndrome)
Malignant Neoplasms:
- Oral
- Encroaching from antrum (sinus) or nose
Drugs
- Cytotoxics
- NSAIDs
- Nicorandil
- Many others
Systemic Disease
Microbial Diseases
- Herpetic Stomatitis
- Chickenpox
- Hand, Foot and Mouth Disease
- Herpangina
- Infectious Mononucleosis
- HIV
- Acute Necrotising Gingivitis
- Tuberculosis (TB)
- Syphilis
- Histoplasmosis
- Cryptococcosis
- Blastomycosis
- Paracoccidioidomycosis
- Leishmaniasis
Muco-Cutaneous Diseases:
- Lichen Planus
- Pemphigus Vulgaris
- Pemphigoid and variants
- Erythema Multiforme
- Dermatitis Herpetiformis
- Linear IgA Disease
- Epidermolysis Bullosa
- Chronic Ulcerative Stomatitis
- other dermatoses
Blood Disorders:
- Anæmia
- Leukæmia
- Myelo-Dysplastic Syndrome
- Neutropænia
- Other White Cell Dyscrasias
- Hæmatinic Deficiencies
- Gammopathies
Gastrointestinal Diseases:
- Cœliac Disease
- Ulcerative Colitis
- Crohn’s Disease
Rheumatic Diseases:
- Lupus Erythematosus
- Reiter Syndrome
- Sweet Syndrome
Vasculitides:
- Behçet Syndrome
- Wegener’s Granulomatosis
- Peri-Arteritis Nodosa
- Giant Cell Arteritis
Endocrine Disorders:
- Diabetes
- Glucagonoma
Disorders of Uncertain Pathogenesis:
- Eosinophilic Ulcer
- Hyper-Eosinophilic Syndrome
- Necrotising Sialometaplasia