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Sjögren’s Syndrome is a systemic auto-immune disease characterised by dry mouth and dry eyes and various auto-immune changes, confirmed by a blood test or salivary gland biopsy.

Sjögren’s Syndrome can occur as an independent, primary condition, ”Primary Sjögren’s Syndrome“ or accompany another auto-immune disease, such as Rheumatoid Arthritis, in which case it is known as “Secondary Sjögren’s Syndrome”.

In addition to dryness of the mucous membranes and skin, Sjögren’s Syndrome can also lead to:

  • general symptoms such as fatigue, musculo-skeletal pain and less commonly
  • pathological changes in internal organs and
  • various complications such as caries (dental decay), candidosis (Thrush) [link to Oral Candidiasis], congenital heart block and lymphoma.

Sjögren’s Syndrome can have profound effects on the mouth (hence its inclusion on this web-site).

This is a broad subject and other people / websites explain it far better than me.

I list here some very useful websites and also a variety of articles about Sjögren’s Syndrome.

Useful Websites:

NHS Direct

Sjögren’s Syndrome Society

British Sjögren’s Syndrome Association

Patient UK

Revised International Classification Criteria for Sjögren’s Syndrome

Emedicine (Connective Tissue Disorders)

Emedicine (Rheumatology)

Emedicine (Rheumatology)

Useful Articles

Dent Update1999. Orofacial Disease. Update for the Dental Clinical Team 8. Salivary Complaints

Ann Rheum Dis 2002.  CONSENSUS REPORT.  Classification criteria for Sjögren’s Syndrome: a revised version of the European criteria proposed by the American-European Consensus Group.

Oral Diseases 2002.  Current Issues in Sjögren’s Syndrome

Am Fam Physician 2009.  Diagnosis & Management of Sjögren’s Syndrome

BMJ 2012.  Practice Pointer.  Primary Sjögren’s Syndrome

BDJ 2012.  Sjögren’s Syndrome – An Update for Dental Practitioners

British Sjögren’s Syndrome Association – Sjögren’s Syndrome

British Sjögren’s Syndrome Association – Diagnosing Sjögren’s Syndrome

British Sjögren’s Syndrome Association – Treatment of Sjögren’s Syndrome

British Sjögren’s Syndrome Association – General Advice on Sjögren’s Syndrome

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) – What is Sjögren’s Syndrome?

Eastman Dental Institute, Oral Medicine Clinic – Provisional Diagnosis of Sjögren’s Syndrome Patient Information Sheet

Eastman Dental Institute, Oral Medicine Clinic – Sjögren’s Syndrome Patient Information Sheet

NIAMS National Institutes of Health Public Health Service U.S. Department of Health and Human Services Questions Answers about Sjögren’s Syndrome